The birth defect lawyers at Davis & Crump are reviewing potential claims for families of children born with severe birth defects or congenital malformations that may have been caused by the prescription of Zofran during pregnancy for morning sickness, nausea or vomiting.


As a result of the drug maker’s failure to warn about the potential pregnancy side effects of Zofran, many children may have experienced severe and potentially life-threatening birth defects and congenital malformations, including:

  • Cleft Lip or Cleft Palate
  • Congenital Heart Defect
  • Kidney Defects
  • Other Birth Defects
  • Wrongful Death

Zofran (ondansetron) is an anti-nausea and vomiting medication that was introduced by GlaxoSmithKline in 1991. While the medication is only approved for treatment of nausea and vomiting symptoms among chemotherapy patients and following surgery, it has been widely used “off-label” as a morning sickness drug. Nausea and vomiting during the first trimester of pregnancy is one of the most common symptoms experienced by pregnant women.

In rare cases, extreme morning sickness can result in hyperemesis gravidarum, which may result in hospitalization, dehydration, malnutrition, fluid or electrolyte imbalances, and other complications.

Despite a lack of evidence establishing Zofran was safe for pregnant women, lawsuits allege that GlaxoSmithKline actively promoted such off-label use and withheld important warnings about the potential link between Zofran and birth defects.

Do you have a Zofran Lawsuit? We can help.

Davis & Crump is now handling claims for individuals who have suffered birth defects from Zofran. Davis & Crump is experienced in pharmaceutical and medical device litigation and settlements. If you or a loved one has been injured by Zofran, call us at 1-800-277-0300 or email us at

Fill out a free claim evaluation or call us at 1-800-277-0300 to get started.